Will I ever get to a point where I can one-hit kill minor creatures?

[Ecolocon]

There isn't so much of a feeling of powering up in this game. . . Is there a build that gets to that point? As a level 41, having to deal with minor creatures harassing me while I'm exploring in PvE gets tiring, especially since the re-spawning is stupidly quick in some cases.

What is really annoying is that if a creature chases me and I run until it stops chasing, then turn around to take it out, many times the thing is invulnerable and regenerates health while it retreats to its original position, where it becomes vulnerable to attacks. It seems that once the creature has moved out of its territory it becomes unkillable.

I feel like a tool with this game at times. (yes , I constantly upgrade my weapons, with dubious benefits)

Seems all the stats and mechanics are tweaked in favour of PvP balance and it cheapens PvE gameplay.